Selection of high-z supernovae candidates

Deep, ground based, optical wide-field supernova searches are capable of detecting a large number of supernovae over a broad redshift range up to z~1.5. While it is practically unfeasible to obtain spectroscopic redshifts of all the supernova candidates right after the discovery, we show that the magnitudes and colors of the host galaxies, as well as the supernovae, can be used to select high-z supernova candidates, for subsequent spectroscopic and photometric follow-up. Using Monte-Carlo simulations we construct criteria for selecting galaxies in well-defined redshift bands. For example, with a selection criteria using B-R and R-I colors we are able to pick out potential host galaxies for which z>0.85 with 80% confidence level and with a selection efficiency of 64-86%. The method was successfully tested using real observations from the HDF. Similarly, we show that that the magnitude and colors of the supernova discovery data can be used to constrain the redshift. With a set of cuts based on V-R and R-I in a search to m_I~25, supernovae at z~1 can be selected in a redshift interval sigma_z <0.15.Comment: 33 pages, 13 figures, accepted for publication in PASP (March 2002 issue

Attitudes Toward Anger Management Scale: Development and Initial Validation

This article describes the development and preliminary validation of the Attitudes Toward Anger Management Scale (ATAMS), a self-report measure of attitudes toward anger management services. Undergraduate volunteers (N = 415) completed an initial version of the instrument. Principal components analysis yielded a two-factor solution. Convergent and incremental validities were supported

The Evolution of the Optical and Near-Infrared Galaxy Luminosity Functions and Luminosity Densities to z~2

Using Hubble Space Telescope and ground-based U through K- band photometry from the Great Observatories Origins Deep Survey (GOODS), we measure the evolution of the luminosity function and luminosity density in the rest-frame optical (UBR) to z ~ 2, bridging the poorly explored ``redshift desert'' between z~1 and z~2. We also use deep near-infrared observations to measure the evolution in the rest-frame J-band to z~1. Compared to local measurements from the SDSS, we find a brightening of the characteristic magnitude, (M*), by ~2.1, \~0.8 and ~0.7 mag between z=0.1 and z=1.9, in U, B, and R bands, respectively. The evolution of M* in the J-band is in the opposite sense, showing a dimming between redshifts z=0.4 and z=0.9. This is consistent with a scenario in which the mean star formation rate in galaxies was higher in the past, while the mean stellar mass was lower, in qualitative agreement with hierarchical galaxy formation models. We find that the shape of the luminosity function is strongly dependent on spectral type and that there is strong evolution with redshift in the relative contribution from the different spectral types to the luminosity density. We find good agreement in the luminosity function derived from an R-selected and a K-selected sample at z~1, suggesting that optically selected surveys of similar depth (R < 24) are not missing a significant fraction of objects at this redshift relative to a near-infrared-selected sample. We compare the rest-frame B-band luminosity functions from z~0--2 with the predictions of a semi-analytic hierarchical model of galaxy formation, and find qualitatively good agreement. In particular, the model predicts at least as many optically luminous galaxies at z~1--2 as are implied by our observations.Comment: 43 pages; 15 Figures; 5 Tables, Accepted for publication in Ap.

A transcriptome-driven analysis of epithelial brushings and bronchial biopsies to define asthma phenotypes in U-BIOPRED

RATIONALE AND OBJECTIVES: Asthma is a heterogeneous disease driven by diverse immunologic and inflammatory mechanisms. We used transcriptomic profiling of airway tissues to help define asthma phenotypes. METHODS: The transcriptome from bronchial biopsies and epithelial brushings of 107 moderate-to-severe asthmatics were annotated by gene-set variation analysis (GSVA) using 42 gene-signatures relevant to asthma, inflammation and immune function. Topological data analysis (TDA) of clinical and histological data was used to derive clusters and the nearest shrunken centroid algorithm used for signature refinement. RESULTS: 9 GSVA signatures expressed in bronchial biopsies and airway epithelial brushings distinguished two distinct asthma subtypes associated with high expression of T-helper type 2 (Th-2) cytokines and lack of corticosteroid response (Group 1 and Group 3). Group 1 had the highest submucosal eosinophils, high exhaled nitric oxide (FeNO) levels, exacerbation rates and oral corticosteroid (OCS) use whilst Group 3 patients showed the highest levels of sputum eosinophils and had a high BMI. In contrast, Group 2 and Group 4 patients had an 86% and 64% probability of having non-eosinophilic inflammation. Using machine-learning tools, we describe an inference scheme using the currently-available inflammatory biomarkers sputum eosinophilia and exhaled nitric oxide levels along with OCS use that could predict the subtypes of gene expression within bronchial biopsies and epithelial cells with good sensitivity and specificity. CONCLUSION: This analysis demonstrates the usefulness of a transcriptomic-driven approach to phenotyping that segments patients who may benefit the most from specific agents that target Th2-mediated inflammation and/or corticosteroid insensitivity

On the Relation Between Peak Luminosity and Parent Population of Type Ia Supernovae: A New Tool for Probing the Ages of Distant Galaxies

We study the properties of Type Ia Supernovae (SNe Ia) as functions of the radial distance from their host galaxy centers. Using a sample of 62 SNe Ia with reliable luminosity, reddening, and decline rate determinations, we find no significant radial gradients of SNe Ia peak absolute magnitudes or decline rates in elliptical+S0 galaxies, suggesting that the diversity of SN properties is not related to the metallicity of their progenitors. We do find that the range in brightness and light curve width of supernovae in spiral galaxies extends to brighter, broader values. These results are interpreted as support for an age, but not metallicity, related origin of the diversity in SNe Ia. If confirmed with a larger and more accurate sample of data, the age-luminosity relation would offer a new and powerful tool to probe the ages and age gradients of stellar populations in galaxies at redshift as high as $z\sim1-2$. The absence of significant radial gradients in the peak $\rm (B-V)_0$ and $\rm (V-I)_0$ colors of SNe Ia supports the redding correction method of Phillips et al (1999). We find no radial gradient in residuals from the SN Ia luminosity-width relation, suggesting that the relation is not affected by properties of the progenitor populations and supporting the reliability of cosmological results based upon the use of SNe Ia as distance indicators.Comment: 19 pages, incl. 3 tables & 3 figures; to appear in Nov 2000 issue of Ap

Relation Between Stellar Mass and Star Formation Activity in Galaxies

For a mass-selected sample of 66544 galaxies with photometric redshifts from the Cosmic Evolution Survey (COSMOS), we examine the evolution of star formation activity as a function of stellar mass in galaxies. We estimate the cosmic star formation rates (SFR) over the range 0.2 < z < 1.2, using the rest-frame 2800 A flux (corrected for extinction). We find the mean SFR to be a strong function of the galactic stellar mass at any given redshift, with massive systems (log (M/M(Sun)) > 10.5) contributing less (by a factor of ~ 5) to the total star formation rate density (SFRD). Combining data from the COSMOS and Gemini Deep Deep Survey (GDDS), we extend the SFRD-z relation as a function of stellar mass to z~2. For massive galaxies, we find a steep increase in the SFRD-z relation to z~2; for the less massive systems, the SFRD which also increases from z=0 to 1, levels off at z~1. This implies that the massive systems have had their major star formation activity at earlier epochs (z > 2) than the lower mass galaxies. We study changes in the SFRDs as a function of both redshift and stellar mass for galaxies of different spectral types. We find that the slope of the SFRD-z relation for different spectral type of galaxies is a strong function of their stellar mass. For low and intermediate mass systems, the main contribution to the cosmic SFRD comes from the star-forming galaxies while, for more massive systems, the evolved galaxies are the most dominant population.Comment: 34 pages; 8 figures; Accepted for publication in Ap

The Age-Redshift Relation for Standard Cosmology

We present compact, analytic expressions for the age-redshift relation $\tau(z)$ for standard Friedmann-Lema\^ \itre-Robertson-Walker (FLRW) cosmology. The new expressions are given in terms of incomplete Legendre elliptic integrals and evaluate much faster than by direct numerical integration.Comment: 13 pages, 3 figure

Warm perineal compresses during the second stage of labor for reducing perineal trauma: A meta-analysis

OBJECTIVE: Perineal trauma may have a negative impact on women's lives as it has been associated with perineal pain, urinary incontinence and sexual dysfunction. The aim of this systematic review and meta-analysis of randomized controlled trials was to evaluate the effectiveness of warm compresses during the second stage of labor in reducing perineal trauma. METHODS: Electronic databases were searched from inception of each database to May 2019. Inclusion criteria were randomized trials comparing warm compresses (i.e. intervention group) with no warm compresses (i.e. control group) during the second stage of labor. Types of participants included pregnant women planning to have a spontaneous vaginal birth at term with a singleton in a cephalic presentation. The primary outcome was the incidence of intact perineum. Meta-analysis was performed using the Cochrane Collaboration methodology with results being reported as relative risk (RR) with 95% confidence interval (CI). RESULTS: Seven trials, including 2103 participants, were included in this meta-analysis. Women assigned to the intervention group received warm compresses made from clean washcloths or perineal pads immersed in warm tap water. These were held against the woman's perineum during and in between pushes in second stage. Warm compresses usually started when the baby's head began to distend the perineum or when there was active fetal descent in the second stage of labor. We found a higher rate of intact perineum in the intervention group compared to the control group (22.4% vs 15.4%; RR 1.46, 95% CI 1.22 to 1.74); a lower rate of third degree tears (1.9% vs 5.0%; RR 0.38, 95% CI 0.22 to 0.64), fourth degree tears (0.0% vs 0.9%; RR 0.11, 95% CI 0.01 to 0.86) third and fourth degree tears combined (1.9% vs 5.8%; RR 0.34, 95% CI 0.20 to 0.56) and episiotomy (10.4% vs 17.1%; RR 0.61, 95% CI 0.51 to 0.74). CONCLUSION: Warm compresses applied during the second stage of labor increase the incidence of intact perineum and lower the risk of episiotomy and severe perineal trauma

Designing Future Dark Energy Space Missions: II. Photometric Redshift of Space Weak Lensing Optimized Survey

Accurate weak-lensing analysis requires not only accurate measurement of galaxy shapes but also precise and unbiased measurement of galaxy redshifts. The photometric redshift technique appears as the only possibility to determine the redshift of the background galaxies used in the weak-lensing analysis. Using the photometric redshift quality, simple shape measurement requirements, and a proper sky model, we explore what could be an optimal weak-lensing dark energy mission based on FoM calculation. We found that photometric redshifts reach their best accuracy for the bulk of the faint galaxy population when filters have a resolution R~3.2. We show that an optimal mission would survey the sky through 8 filters using 2 cameras (visible and near infrared). Assuming a 5-year mission duration, a mirror size of 1.5m, a 0.5deg2 FOV with a visible pixel scale of 0.15", we found that a homogeneous survey reaching IAB=25.6 (10sigma) with a sky coverage of ~11000deg2 maximizes the Weak Lensing FoM. The effective number density of galaxies then used for WL is ~45gal/arcmin2, at least a factor of two better than ground based survey. This work demonstrates that a full account of the observational strategy is required to properly optimize the instrument parameters to maximize the FoM of the future weak-lensing space dark energy mission.Comment: 25 pages, 39 figures, accepted in A&